Xiaolin Tong

Tong Xiaolin, a Chinese Academy of Sciences academician and an internal medicine expert in traditional Chinese medicine, serves as the Director of the National Center for Integrative Medicine. He has dedicated himself to the inheritance and innovative research of traditional Chinese medicine, integrating the Chinese medicine approach of “harmonization” with the Western medicine approach of “targeted therapy,” introducing the concept of “harmony-target-differentiation-treatment.” This has led to the reconstruction of a new diagnostic and treatment system in traditional Chinese medicine and the modern herbal medicine.

He has developed effective treatment formulas for diabetes at different stages, and his achievements have been incorporated into international and domestic guidelines for traditional Chinese medicine. Addressing a crucial factor affecting the effectiveness of traditional Chinese medicine – the dosage of herbal medicine, he has established the discipline of Traditional Chinese Medicine Dose-Response, providing dosage standards and scientific foundations for rational drug use, significantly improving the efficacy in critical and severe cases.

He has received various honors, including the national “Most Beautiful Scientific Worker” from the Publicity Department of the Communist Party of China, the Second National Innovation Award from the Ministry of Human Resources and Social Security, and recognition as an “Advanced Individual in the Fight Against COVID-19” by the Central Committee of the Communist Party of China. Additionally, he has been awarded the title of “Teaching Master of Traditional Chinese Medicine Colleges” by the National Administration of Traditional Chinese Medicine, the Ministry of Education, and the National Health Commission.


State-target Differentiation and Treatment.


State-target Differentiation and Treatment is a thought process that integrates Western and traditional Chinese medicine. On one hand, it involves diagnosing diseases according to Western medicine’s disease names, considering the complete development of diseases, and reevaluating diseases with traditional Chinese medicine diagnostic thinking. This involves classifying diseases, staging them, and differentiating symptoms, understanding the core causes and mechanisms of diseases, and combining symptoms with treatment strategies and targeted medication.

On the other hand, it draws from microscopic examination and utilizes disciplines such as cell and molecular biology, anatomy, and pharmacology. It extends traditional Chinese medicine’s four diagnostic methods by combining the traditional Chinese medicine harmonization approach with micro-targeted therapy, allowing for precise medication and improving the specificity and accuracy of treatment.

The construction of the Harmony-Target-Differentiation-Treatment system provides a new model for clinical diagnosis and treatment in traditional Chinese medicine. While guiding clinical treatment and medication selection, proper dosage is crucial for maximizing the efficacy of targeted treatment. Clinical drug dosages should fall within the range specified in the “Chinese Pharmacopoeia” and the broad dosing thresholds defined in classical medical texts, achieving a balance between the disease and its treatment, with the treatment dosage chosen based on expected outcomes.